As Benjamin Hurlbut recommends, social agreement on gene-editing applications should draw from “diverse customs of idea” ( Nature565, 135; 2019). Considered that Muslims comprise one-quarter of the worldwide community today, we offer an Islamic point of view to enrich the discussion on the ethical issues developing from the birth of CRISPR gene-edited human twins in 2015.
Research approach in traditional Islamic scholarship utilizes five concepts to resolve such ethical dilemmas. The very first, Qasd, associates with intent– valid in this case, if the aim was to enhance social well-being by protecting the twins against transmission of HIV from their infected father. The second principle, Yaqin, issues certainty; however, the long-term security of CRISPR innovation is unsure. The 3rd, Darar, alludes to the avoidance of injury; here, the balance of threat and advantage to the twins and their progeny is not yet comprehended, therefore the moms and dads’ authorization was not effectively informed. The 4th, Darura, describes need– doubtful in this case, since established and safe alternatives exist for securing individuals from HIV. The final concept, Urf, connects to custom– in this circumstances, to the social context and acceptance of using the innovation; and the public is anxious about gene editing.
This viewpoint supplied the ethical compass that allowed science to flourish throughout the midlifes in the Islamic civilization, on which Western science partly stands today (see, for example, J. Al-Khalili Nature 518, 164–165; 2015).
Nature566, 455 (2019)
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